Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXMI6F
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| Drug Name |
N-{(S)-1-[(R)-1-Formyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-2-methyl-butyl}-benzamide
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| Synonyms |
CHEMBL1790996
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H27N3O3
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| Canonical SMILES |
CC[C@@H](C)[C@H](NC(=O)c1ccccc1)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C=O
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| InChI |
InChI=1S/C24H27N3O3/c1-3-16(2)22(27-23(29)17-9-5-4-6-10-17)24(30)26-19(15-28)13-18-14-25-21-12-8-7-11-20(18)21/h4-12,14-16,19,22,25H,3,13H2,1-2H3,(H,26,30)(H,27,29)/t16-,19-,22+/m1/s1
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| InChIKey |
XALMMLXCBLXHHZ-PERKRYKHSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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