Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXM6WP
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| Drug Name |
(S)-1-(5,6-dichloro-1H-benzo[d]imidazol-1-yl)-3,3-dimethylbutan-2-yl (S)-3-oxo-4-(pyridine-2-sulfonamido)butan-2-ylcarbamate
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| Synonyms |
CHEMBL232712
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H27Cl2N5O5S
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| Canonical SMILES |
C[C@H](NC(=O)O[C@H](Cn1cnc2cc(Cl)c(Cl)cc12)C(C)(C)C)C(=O)CNS(=O)(=O)c3ccccn3
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| InChI |
InChI=1S/C23H27Cl2N5O5S/c1-14(19(31)11-28-36(33,34)21-7-5-6-8-26-21)29-22(32)35-20(23(2,3)4)12-30-13-27-17-9-15(24)16(25)10-18(17)30/h5-10,13-14,20,28H,11-12H2,1-4H3,(H,29,32)/t14-,20+/m0/s1
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| InChIKey |
SYBYCMXFKUMMNW-VBKZILBWSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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