Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXM6JE
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| Drug Name |
N-(4-methyl-3-(3-(2-(methylamino)pyridin-4-yl)pyridin-2-yloxy)phenyl)-3-(1,1,2,2-tetrafluoroethoxy)benzamide
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| Synonyms |
CHEMBL397090
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H22F4N4O3
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| Canonical SMILES |
CNc1cc(ccn1)c2cccnc2Oc3cc(NC(=O)c4cccc(OC(F)(F)C(F)F)c4)ccc3C
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| InChI |
InChI=1S/C27H22F4N4O3/c1-16-8-9-19(35-24(36)18-5-3-6-20(13-18)38-27(30,31)26(28)29)15-22(16)37-25-21(7-4-11-34-25)17-10-12-33-23(14-17)32-2/h3-15,26H,1-2H3,(H,32,33)(H,35,36)
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| InChIKey |
BOECRTNECUVVNV-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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