Drug Information

Drug General Information
Drug ID
DXM5TE
Drug Name
CHEMBL2094104
Indication Discovery agent Investigative [1587926]
Formula
C28H28ClF2NO
Canonical SMILES
CN1C2CCC1[C@H](COC(c3ccc(F)cc3)c4ccc(F)cc4)C(C2)c5ccc(Cl)cc5
InChI
InChI=1S/C28H28ClF2NO/c1-32-24-14-15-27(32)26(25(16-24)18-2-8-21(29)9-3-18)17-33-28(19-4-10-22(30)11-5-19)20-6-12-23(31)13-7-20/h2-13,24-28H,14-17H2,1H3/t24?,25?,26-,27?/m1/s1
InChIKey
MJIUURUOIXCZBF-GGYOGJIUSA-N
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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