Drug Information

Drug General Information
Drug ID
DXL0S6
Drug Name
(S)-2-[3-({(4-Cyano-benzyl)-[3-(4-cyano-benzyl)-3H-imidazol-4-ylmethyl]-amino}-methyl)-benzoylamino]-4-methylsulfanyl-butyric acid
Synonyms
CHEMBL61785
Indication Discovery agent Investigative [1587926]
Formula
C33H32N6O3S
Canonical SMILES
CSCC[C@H](NC(=O)c1cccc(CN(Cc2ccc(cc2)C#N)Cc3cncn3Cc4ccc(cc4)C#N)c1)C(=O)O
InChI
InChI=1S/C33H32N6O3S/c1-43-14-13-31(33(41)42)37-32(40)29-4-2-3-28(15-29)20-38(19-26-9-5-24(16-34)6-10-26)22-30-18-36-23-39(30)21-27-11-7-25(17-35)8-12-27/h2-12,15,18,23,31H,13-14,19-22H2,1H3,(H,37,40)(H,41,42)/t31-/m0/s1
InChIKey
UYKAYMDFMOZSIG-HKBQPEDESA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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