Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXK0RP
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| Drug Name |
(S)-2-(3-Benzyl-ureido)-3-methyl-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide
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| Synonyms |
CHEMBL1790990
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C25H30N4O3
|
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| Canonical SMILES |
CC[C@@H](C)[C@H](NC(=O)NCc1ccccc1)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C=O
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| InChI |
InChI=1S/C25H30N4O3/c1-3-17(2)23(29-25(32)27-14-18-9-5-4-6-10-18)24(31)28-20(16-30)13-19-15-26-22-12-8-7-11-21(19)22/h4-12,15-17,20,23,26H,3,13-14H2,1-2H3,(H,28,31)(H2,27,29,32)/t17-,20-,23+/m1/s1
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| InChIKey |
MIJCHWHMTSWDNO-LLBVYWAGSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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