Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXJF9U
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| Drug Name |
{1-[2-Oxo-1-phenethyl-3-(3-phenyl-propylsulfanyl)-propylcarbamoyl]-2-phenyl-ethyl}-carbamic acid pyridin-3-ylmethyl ester
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| Synonyms |
CHEMBL347459
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C36H39N3O4S
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| Canonical SMILES |
O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCc2ccccc2)C(=O)CSCCCc3ccccc3)OCc4cccnc4
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| InChI |
InChI=1S/C36H39N3O4S/c40-34(27-44-23-11-19-28-12-4-1-5-13-28)32(21-20-29-14-6-2-7-15-29)38-35(41)33(24-30-16-8-3-9-17-30)39-36(42)43-26-31-18-10-22-37-25-31/h1-10,12-18,22,25,32-33H,11,19-21,23-24,26-27H2,(H,38,41)(H,39,42)/t32-,33-/m0/s1
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| InChIKey |
VZRKGDOTBQOIIT-LQJZCPKCSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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