Drug Information

Drug General Information
Drug ID
DXI3BK
Drug Name
4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1-carboxylic acid (1-oxy-pyridin-3-yl)-amide
Synonyms
CHEMBL171597
Indication Discovery agent Investigative [1587926]
Formula
C24H24ClN5O2
Canonical SMILES
[O-][n+]1cccc(NC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cccnc35)c1
InChI
InChI=1S/C24H24ClN5O2/c25-19-7-8-21-18(15-19)6-5-17-3-1-9-26-22(17)23(21)28-11-13-29(14-12-28)24(31)27-20-4-2-10-30(32)16-20/h1-4,7-10,15-16,23H,5-6,11-14H2,(H,27,31)
InChIKey
OQWJKOITLPKNGK-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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