Drug Information

Drug General Information
Drug ID
DXH0ZI
Drug Name
rac-1-(4-(but-2-ynyloxy)phenylsulfonyl)piperidine-3-thiol
Synonyms
CHEMBL243236
Indication Discovery agent Investigative [1587926]
Formula
C15H19NO3S2
Canonical SMILES
CC#CCOc1ccc(cc1)S(=O)(=O)N2CCCC(S)C2
InChI
InChI=1S/C15H19NO3S2/c1-2-3-11-19-13-6-8-15(9-7-13)21(17,18)16-10-4-5-14(20)12-16/h6-9,14,20H,4-5,10-12H2,1H3
InChIKey
NVJUVGMOOGFJLZ-UHFFFAOYSA-N
Target and Pathway
Target(s) Collagenase 3 Target Info [1587926]
Neutrophil collagenase Target Info [1587926]
NetPath Pathway IL1 Signaling Pathway
PANTHER Pathway Alzheimer disease-presenilin pathway
Plasminogen activating cascadeP00004:Alzheimer disease-presenilin pathway
Pathway Interaction Database Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Assembly of collagen fibrils and other multimeric structuresR-HSA-1442490:Collagen degradation
WikiPathways Endochondral Ossification
Activation of Matrix Metalloproteinases
Oncostatin M Signaling Pathway
AGE/RAGE pathway
Matrix MetalloproteinasesWP2769:Activation of Matrix Metalloproteinases
Matrix Metalloproteinases
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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