Drug General Information
Drug ID
DXF3IL
Drug Name
[3-(1H-Indol-2-yl)-propyl]-[2-(2-methoxy-phenoxy)-ethyl]-amine
Synonyms
CHEMBL2112645
Indication Discovery agent Investigative [1587926]
Formula
C20H24N2O2
Canonical SMILES
COc1ccccc1OCCNCCCc2c[nH]c3ccccc23
InChI
InChI=1S/C20H24N2O2/c1-23-19-10-4-5-11-20(19)24-14-13-21-12-6-7-16-15-22-18-9-3-2-8-17(16)18/h2-5,8-11,15,21-22H,6-7,12-14H2,1H3
InChIKey
STPTYZMDTOSUMZ-UHFFFAOYSA-N
Target and Pathway
Target(s) 5-hydroxytryptamine 1A receptor Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapsehsa04726:Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathwayP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signalingWP727:Monoamine Transport
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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