Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXEH4S
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| Drug Name |
3-{2-cyano-2-[1-(3-methyloxycarbonylanilino)-2-(3-methylphenyl)-(1S)-ethylcarboxamido]ethoxymethyl}benzoic acid
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| Synonyms |
CHEMBL336115
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H29N3O6
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| Canonical SMILES |
COC(=O)c1cccc(N[C@@H](Cc2cccc(C)c2)C(=O)N[C@@H](COCc3cccc(c3)C(=O)O)C#N)c1
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| InChI |
InChI=1S/C29H29N3O6/c1-19-6-3-7-20(12-19)14-26(31-24-11-5-10-23(15-24)29(36)37-2)27(33)32-25(16-30)18-38-17-21-8-4-9-22(13-21)28(34)35/h3-13,15,25-26,31H,14,17-18H2,1-2H3,(H,32,33)(H,34,35)/t25-,26+/m1/s1
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| InChIKey |
YKGCZJXHFVVNSC-FTJBHMTQSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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