Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXD5BQ
|
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| Drug Name |
2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid [2-(4-methoxy-phenyl)-ethyl]-amide
|
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| Synonyms |
CHEMBL220496
|
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C20H25N5O2
|
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| Canonical SMILES |
COc1ccc(CCNC(=O)c2cnc(nc2NCC(C)(C)C)C#N)cc1
|
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| InChI |
InChI=1S/C20H25N5O2/c1-20(2,3)13-24-18-16(12-23-17(11-21)25-18)19(26)22-10-9-14-5-7-15(27-4)8-6-14/h5-8,12H,9-10,13H2,1-4H3,(H,22,26)(H,23,24,25)
|
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| InChIKey |
GUUHOTXBVVLLAX-UHFFFAOYSA-N
|
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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