Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXCC5F
|
||||
| Drug Name |
methyl N-(5-(5-((2-fluoro-5-(trifluoromethyl)phenyl)aminocarbonylamino)-2-pyridyloxy)-1H-benzimidazol-2-yl)carbamate
|
||||
| Synonyms |
CHEMBL243910
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H16F4N6O4
|
||||
| Canonical SMILES |
COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cn3)cc2[nH]1
|
||||
| InChI |
InChI=1S/C22H16F4N6O4/c1-35-21(34)32-19-29-15-6-4-13(9-17(15)30-19)36-18-7-3-12(10-27-18)28-20(33)31-16-8-11(22(24,25)26)2-5-14(16)23/h2-10H,1H3,(H2,28,31,33)(H2,29,30,32,34)
|
||||
| InChIKey |
VSMMGESTZLCGTL-UHFFFAOYSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.