Drug Information
| Drug General Information | |||||
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| Drug ID |
DXC7UT
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| Drug Name |
7-[(1E)-1-(ethoxyimino)ethyl]-19-methyl-3-(2-methylpropyl)-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-14-one
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| Synonyms |
CHEMBL428433
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H31N5O2
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| Canonical SMILES |
CCO\\N=C(/C)\\c1ccc2c(c1)c3c4CNC(=O)c4c5c(CCc6nn(C)cc56)c3n2CC(C)C
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| InChI |
InChI=1S/C28H31N5O2/c1-6-35-31-16(4)17-7-10-23-19(11-17)25-20-12-29-28(34)26(20)24-18(27(25)33(23)13-15(2)3)8-9-22-21(24)14-32(5)30-22/h7,10-11,14-15H,6,8-9,12-13H2,1-5H3,(H,29,34)/b31-16+
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| InChIKey |
RQJXNGZLPCZKFS-WCMJOSRZSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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