Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXC2RO
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| Drug Name |
5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazol-5-yl)-N-(3-(trifluoromethoxy)phenyl)-1,3,4-oxadiazol-2-amine
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| Synonyms |
CHEMBL206538
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C19H16F3N7O2
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| Canonical SMILES |
Cn1cnc(NCc2ccncc2)c1c3oc(Nc4cccc(OC(F)(F)F)c4)nn3
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| InChI |
InChI=1S/C19H16F3N7O2/c1-29-11-25-16(24-10-12-5-7-23-8-6-12)15(29)17-27-28-18(30-17)26-13-3-2-4-14(9-13)31-19(20,21)22/h2-9,11,24H,10H2,1H3,(H,26,28)
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| InChIKey |
BNRFCNNNVLUTOS-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Vascular endothelial growth factor receptor 1 | Target Info | [1587926] | |||
| KEGG Pathway | Ras signaling pathway | ||||
| Rap1 signaling pathway | |||||
| Cytokine-cytokine receptor interaction | |||||
| Endocytosis | |||||
| PI3K-Akt signaling pathway | |||||
| VEGF signaling pathway | |||||
| Focal adhesion | |||||
| Proteoglycans in cancerhsa04014:Ras signaling pathway | |||||
| HIF-1 signaling pathway | |||||
| Transcriptional misregulation in cancer | |||||
| Rheumatoid arthritis | |||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathway | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkglypican_1pathway:Glypican 1 network | |||||
| S1P3 pathway | |||||
| VEGFR1 specific signals | |||||
| References | |||||
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