Drug Information

Drug General Information
Drug ID
DXB8MD
Drug Name
1-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-methyl-2-(1-oxy-pyridin-3-yl)-propan-1-one
Synonyms
CHEMBL171484
Indication Discovery agent Investigative [1587926]
Formula
C27H28BrClN4O2
Canonical SMILES
CC(C)(C(=O)N1CCN(CC1)C2c3ccc(Cl)cc3CCc4cc(Br)cnc24)c5ccc[n+]([O-])c5
InChI
InChI=1S/C27H28BrClN4O2/c1-27(2,20-4-3-9-33(35)17-20)26(34)32-12-10-31(11-13-32)25-23-8-7-22(29)15-18(23)5-6-19-14-21(28)16-30-24(19)25/h3-4,7-9,14-17,25H,5-6,10-13H2,1-2H3
InChIKey
LKJVJLHCXBTZOM-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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