Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DXAB3K
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| Drug Name |
N-(3-(4-amino-5-(4-methoxyphenyl)furo[2,3-d]pyrimidin-6-yl)phenyl)methanesulfonamide
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| Synonyms |
CHEMBL194150
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C20H18N4O4S
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| Canonical SMILES |
COc1ccc(cc1)c2c(oc3ncnc(N)c23)c4cccc(NS(=O)(=O)C)c4
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| InChI |
InChI=1S/C20H18N4O4S/c1-27-15-8-6-12(7-9-15)16-17-19(21)22-11-23-20(17)28-18(16)13-4-3-5-14(10-13)24-29(2,25)26/h3-11,24H,1-2H3,(H2,21,22,23)
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| InChIKey |
QSUZLYWASFSPHS-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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