Drug General Information
Drug ID
DX9NM6
Drug Name
((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-methyl-(2-quinoxalin-6-yl-ethyl)-amine
Synonyms
CHEMBL9924
Indication Discovery agent Investigative [1587926]
Formula
C23H27N3O
Canonical SMILES
COc1cccc2[C@H](CN(C)CCc3ccc4nccnc4c3)CCCc12
InChI
InChI=1S/C23H27N3O/c1-26(14-11-17-9-10-21-22(15-17)25-13-12-24-21)16-18-5-3-7-20-19(18)6-4-8-23(20)27-2/h4,6,8-10,12-13,15,18H,3,5,7,11,14,16H2,1-2H3/t18-/m0/s1
InChIKey
OEMXCGIPZRQFGM-SFHVURJKSA-N
Target and Pathway
Target(s) 5-hydroxytryptamine 1B receptor Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapsehsa04726:Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathwayP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signalingWP727:Monoamine Transport
SIDS Susceptibility Pathways
NRF2 pathway
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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