Drug Information
Drug General Information | |||||
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Drug ID |
DX9KBI
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Drug Name |
N-[19-methyl-3-(2-methylpropyl)-14-oxo-3,13,19,20-tetraazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,21}]tricosa-1(16),2(10),4,6,8,11(15),17,20-octaen-7-yl]thiophene-2-carboxamide
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Synonyms |
CHEMBL426703
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Indication | Discovery agent | Investigative | [1587926] | ||
Formula |
C29H27N5O2S
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Canonical SMILES |
CC(C)Cn1c2ccc(NC(=O)c3cccs3)cc2c4c5CNC(=O)c5c6c(CCc7nn(C)cc67)c14
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InChI |
InChI=1S/C29H27N5O2S/c1-15(2)13-34-22-9-6-16(31-28(35)23-5-4-10-37-23)11-18(22)25-19-12-30-29(36)26(19)24-17(27(25)34)7-8-21-20(24)14-33(3)32-21/h4-6,9-11,14-15H,7-8,12-13H2,1-3H3,(H,30,36)(H,31,35)
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InChIKey |
UONXSPFZCSFDNX-UHFFFAOYSA-N
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Target and Pathway | |||||
Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
Angiopoietin 1 receptor | Target Info | [1587926] | |||
NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
PANTHER Pathway | Angiogenesis | ||||
VEGF signaling pathwayP00005:Angiogenesis | |||||
Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
Beta3 integrin cell surface interactions | |||||
Signaling events mediated by TCPTP | |||||
SHP2 signaling | |||||
S1P1 pathway | |||||
VEGF and VEGFR signaling network | |||||
Integrins in angiogenesis | |||||
Signaling events mediated by VEGFR1 and VEGFR2 | |||||
Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
References |
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