Drug Information

Drug General Information
Drug ID
DX9FAI
Drug Name
3-{2-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid amide
Synonyms
CHEMBL169435
Indication Discovery agent Investigative [1587926]
Formula
C26H32ClN5O2
Canonical SMILES
NC(=O)N1CCCC(CC(=O)N2CCN(CC2)C3c4ccc(Cl)cc4CCc5cccnc35)C1
InChI
InChI=1S/C26H32ClN5O2/c27-21-7-8-22-20(16-21)6-5-19-4-1-9-29-24(19)25(22)31-13-11-30(12-14-31)23(33)15-18-3-2-10-32(17-18)26(28)34/h1,4,7-9,16,18,25H,2-3,5-6,10-15,17H2,(H2,28,34)
InChIKey
ZFMMYZMTTNRMCF-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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