Drug Information

Drug General Information
Drug ID
DX8LHS
Drug Name
4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-N'-pyridin-3-ylmethyl-piperidine-1-carboxamidine
Synonyms
CHEMBL157570
Indication Discovery agent Investigative [1587926]
Formula
C27H24BrClN6
Canonical SMILES
Clc1ccc2C(=C3CCN(CC3)\\C(=N/Cc4cccnc4)\\NC#N)c5ncc(Br)cc5CCc2c1
InChI
InChI=1S/C27H24BrClN6/c28-22-12-21-4-3-20-13-23(29)5-6-24(20)25(26(21)32-16-22)19-7-10-35(11-8-19)27(34-17-30)33-15-18-2-1-9-31-14-18/h1-2,5-6,9,12-14,16H,3-4,7-8,10-11,15H2,(H,33,34)
InChIKey
MSYWKAUBOIFIPF-UHFFFAOYSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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