Drug Information

Drug General Information
Drug ID
DX8G9E
Drug Name
(R)-2-Amino-3-(biphenyl-4-ylamino)-propane-1-thiol
Synonyms
FTI-268; CHEMBL55527
Indication Discovery agent Investigative [1587926]
Formula
C15H18N2S
Canonical SMILES
N[C@@H](CS)CNc1ccc(cc1)c2ccccc2
InChI
InChI=1S/C15H18N2S/c16-14(11-18)10-17-15-8-6-13(7-9-15)12-4-2-1-3-5-12/h1-9,14,17-18H,10-11,16H2/t14-/m1/s1
InChIKey
LTTNTQLMUPSHOL-CQSZACIVSA-N
Target and Pathway
Target(s) Farnesyltransferase Target Info [1587926]
Protein farnesyltransferase beta subunit Target Info [1587926]
KEGG Pathway Terpenoid backbone biosynthesis
Biosynthesis of antibioticshsa00900:Terpenoid backbone biosynthesis
Biosynthesis of antibiotics
NetPath Pathway TSH Signaling Pathway
Reactome Apoptotic cleavage of cellular proteins
Inactivation, recovery and regulation of the phototransduction cascadeR-HSA-2514859:Inactivation, recovery and regulation of the phototransduction cascade
WikiPathways Visual phototransduction
Apoptotic execution phaseWP2776:Visual phototransduction
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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