Drug Information
| Drug General Information | |||||
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| Drug ID |
DX8FOO
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| Drug Name |
(S)-3,3-dimethyl-1-(3-(pyridin-4-yl)-1H-pyrazol-1-yl)butan-2-yl (S)-2-oxo-1-(pyridine-2-sulfonamido)heptan-3-ylcarbamate
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| Synonyms |
CHEMBL393354
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H36N6O5S
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| Canonical SMILES |
CCCC[C@H](NC(=O)O[C@H](Cn1ccc(n1)c2ccncc2)C(C)(C)C)C(=O)CNS(=O)(=O)c3ccccn3
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| InChI |
InChI=1S/C27H36N6O5S/c1-5-6-9-22(23(34)18-30-39(36,37)25-10-7-8-14-29-25)31-26(35)38-24(27(2,3)4)19-33-17-13-21(32-33)20-11-15-28-16-12-20/h7-8,10-17,22,24,30H,5-6,9,18-19H2,1-4H3,(H,31,35)/t22-,24+/m0/s1
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| InChIKey |
NHFKTEZZOWFJBK-LADGPHEKSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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