Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX8AE3
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| Drug Name |
((S)-3-Methyl-1-{2-[4-(tetrahydro-pyran-4-yloxy)-phenylamino]-ethylcarbamoyl}-butyl)-carbamic acid benzyl ester
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| Synonyms |
CHEMBL64634
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C27H37N3O5
|
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| Canonical SMILES |
CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)NCCNc2ccc(OC3CCOCC3)cc2
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| InChI |
InChI=1S/C27H37N3O5/c1-20(2)18-25(30-27(32)34-19-21-6-4-3-5-7-21)26(31)29-15-14-28-22-8-10-23(11-9-22)35-24-12-16-33-17-13-24/h3-11,20,24-25,28H,12-19H2,1-2H3,(H,29,31)(H,30,32)/t25-/m0/s1
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| InChIKey |
LHIKIUGGPSXLJE-VWLOTQADSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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