Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX7VEL
|
||||
| Drug Name |
[(S)-2-(3-Fluoro-phenyl)-1-((5S,6R)-4,4,7-trioxo-4lambda*6*-thia-1-aza-bicyclo[3.2.0]hept-6-ylcarbamoyl)-ethyl]-carbamic acid benzyl ester
|
||||
| Synonyms |
CHEMBL116041
|
||||
| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C22H22FN3O6S
|
||||
| Canonical SMILES |
Fc1cccc(C[C@H](NC(=O)OCc2ccccc2)C(=O)N[C@H]3[C@H]4N(CCS4(=O)=O)C3=O)c1
|
||||
| InChI |
InChI=1S/C22H22FN3O6S/c23-16-8-4-7-15(11-16)12-17(24-22(29)32-13-14-5-2-1-3-6-14)19(27)25-18-20(28)26-9-10-33(30,31)21(18)26/h1-8,11,17-18,21H,9-10,12-13H2,(H,24,29)(H,25,27)/t17-,18+,21-/m0/s1
|
||||
| InChIKey |
FNEUKBQFZSGMQF-UEXGIBASSA-N
|
||||
| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.