Drug Information
| Drug General Information | |||||
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| Drug ID |
DX7C6Q
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| Drug Name |
(S)-3,3-dimethyl-1-(3-(4-(trifluoromethyl)phenyl)-1H-pyrazol-1-yl)butan-2-yl (S)-3-oxo-4-(pyridine-2-sulfonamido)butan-2-ylcarbamate
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| Synonyms |
CHEMBL540964
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H30F3N5O5S
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| Canonical SMILES |
C[C@H](NC(=O)O[C@H](Cn1ccc(n1)c2ccc(cc2)C(F)(F)F)C(C)(C)C)C(=O)CNS(=O)(=O)c3ccccn3
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| InChI |
InChI=1S/C26H30F3N5O5S/c1-17(21(35)15-31-40(37,38)23-7-5-6-13-30-23)32-24(36)39-22(25(2,3)4)16-34-14-12-20(33-34)18-8-10-19(11-9-18)26(27,28)29/h5-14,17,22,31H,15-16H2,1-4H3,(H,32,36)/t17-,22+/m0/s1
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| InChIKey |
KCXVQPRWXYAYNA-HTAPYJJXSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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