Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX6K0N
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| Drug Name |
2-(4-Acetylphenylureido)-1-(4-methoxyphenyl)-6,7-methylenedioxy-2H-isoquinolin-3-one
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| Synonyms |
CHEMBL594623
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C26H21N3O6
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| Canonical SMILES |
COc1ccc(cc1)C2=C3C=C4OCOC4=CC3=CC(=O)N2NC(=O)Nc5ccc(cc5)C(=O)C
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| InChI |
InChI=1S/C26H21N3O6/c1-15(30)16-3-7-19(8-4-16)27-26(32)28-29-24(31)12-18-11-22-23(35-14-34-22)13-21(18)25(29)17-5-9-20(33-2)10-6-17/h3-13H,14H2,1-2H3,(H2,27,28,32)
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| InChIKey |
BMSSNHJLONKLJW-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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