Drug Information

Drug General Information
Drug ID
DX5CLL
Drug Name
(R)-5-(4-Methoxy-benzenesulfonyl)-1-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid
Synonyms
CHEMBL292636
Indication Discovery agent Investigative [1587926]
Formula
C15H17N3O5S
Canonical SMILES
COc1ccc(cc1)S(=O)(=O)N2Cc3ncn(C)c3C[C@@H]2C(=O)O
InChI
InChI=1S/C15H17N3O5S/c1-17-9-16-12-8-18(14(15(19)20)7-13(12)17)24(21,22)11-5-3-10(23-2)4-6-11/h3-6,9,14H,7-8H2,1-2H3,(H,19,20)/t14-/m1/s1
InChIKey
FSKXYSMYBLXDDL-CQSZACIVSA-N
Target and Pathway
Target(s) Stromelysin-1 Target Info [1587926]
Neutrophil collagenase Target Info [1587926]
KEGG Pathway TNF signaling pathway
Transcriptional misregulation in cancer
Rheumatoid arthritis
NetPath Pathway IL1 Signaling Pathway
IL4 Signaling Pathway
PANTHER Pathway Plasminogen activating cascade
CCKR signaling map STP00004:Alzheimer disease-presenilin pathway
Pathway Interaction Database Posttranslational regulation of adherens junction stability and dissassembly
p75(NTR)-mediated signaling
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
Reactome Collagen degradation
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Assembly of collagen fibrils and other multimeric structures
EGFR Transactivation by GastrinR-HSA-1442490:Collagen degradation
WikiPathways Activation of Matrix Metalloproteinases
Gastrin-CREB signalling pathway via PKC and MAPK
Oncostatin M Signaling Pathway
Matrix MetalloproteinasesWP2769:Activation of Matrix Metalloproteinases
Matrix Metalloproteinases
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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