Drug Information
| Drug General Information | |||||
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| Drug ID |
DX4TWZ
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| Drug Name |
(S)-3,3-dimethyl-1-(3-(4-(trifluoromethyl)phenyl)-1H-pyrazol-1-yl)butan-2-yl (S)-1-(6-fluoropyridin-2-ylamino)-2-oxoheptan-3-ylcarbamate
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| Synonyms |
CHEMBL232911
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C29H35F4N5O3
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| Canonical SMILES |
CCCC[C@H](NC(=O)O[C@H](Cn1ccc(n1)c2ccc(cc2)C(F)(F)F)C(C)(C)C)C(=O)CNc3cccc(F)n3
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| InChI |
InChI=1S/C29H35F4N5O3/c1-5-6-8-22(23(39)17-34-26-10-7-9-25(30)36-26)35-27(40)41-24(28(2,3)4)18-38-16-15-21(37-38)19-11-13-20(14-12-19)29(31,32)33/h7,9-16,22,24H,5-6,8,17-18H2,1-4H3,(H,34,36)(H,35,40)/t22-,24+/m0/s1
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| InChIKey |
AIBOMLIMFLTQOS-LADGPHEKSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | RANKL/RANK Signaling Pathway | ||||
| Osteoclast Signaling | |||||
| References | |||||
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