Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX4PMN
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| Drug Name |
3-(2-(3H-imidazo[4,5-b]pyridin-6-yl)ethynyl)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide
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| Synonyms |
CHEMBL375840
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H15F3N4O
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| Canonical SMILES |
Cc1ccc(cc1C#Cc2cnc3[nH]cnc3c2)C(=O)Nc4cccc(c4)C(F)(F)F
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| InChI |
InChI=1S/C23H15F3N4O/c1-14-5-7-17(22(31)30-19-4-2-3-18(11-19)23(24,25)26)10-16(14)8-6-15-9-20-21(27-12-15)29-13-28-20/h2-5,7,9-13H,1H3,(H,30,31)(H,27,28,29)
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| InChIKey |
OCMPABRPNWBHCC-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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