Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX4NXE
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| Drug Name |
N-(4-methyl-3-(3-(4-(methylamino)-1,3,5-triazin-2-yl)pyridin-2-yloxy)phenyl)-3-(trifluoromethoxy)benzamide
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| Synonyms |
CHEMBL246152
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H19F3N6O3
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| Canonical SMILES |
CNc1ncnc(n1)c2cccnc2Oc3cc(NC(=O)c4cccc(OC(F)(F)F)c4)ccc3C
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| InChI |
InChI=1S/C24H19F3N6O3/c1-14-8-9-16(32-21(34)15-5-3-6-17(11-15)36-24(25,26)27)12-19(14)35-22-18(7-4-10-29-22)20-30-13-31-23(28-2)33-20/h3-13H,1-2H3,(H,32,34)(H,28,30,31,33)
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| InChIKey |
CLLIAZGFVKRLRZ-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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