Drug Information

Drug General Information
Drug ID
DX4KU1
Drug Name
(3S,4R)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxylic acid 4-[(4-trifluoromethyl-benzoylamino)-methyl]-benzylamide
Synonyms
CHEMBL91574
Indication Discovery agent Investigative [1587926]
Formula
C29H29ClF3N3O2
Canonical SMILES
CN1CC[C@H]([C@@H](C1)C(=O)NCc2ccc(CNC(=O)c3ccc(cc3)C(F)(F)F)cc2)c4ccc(Cl)cc4
InChI
InChI=1S/C29H29ClF3N3O2/c1-36-15-14-25(21-8-12-24(30)13-9-21)26(18-36)28(38)35-17-20-4-2-19(3-5-20)16-34-27(37)22-6-10-23(11-7-22)29(31,32)33/h2-13,25-26H,14-18H2,1H3,(H,34,37)(H,35,38)/t25-,26+/m0/s1
InChIKey
VINPBPAOFNCDSB-IZZNHLLZSA-N
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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