Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX3U8D
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| Drug Name |
7-Cyclopentyl-6-morpholin-4-ylmethyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine
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| Synonyms |
CHEMBL68663
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H31N5O2
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| Canonical SMILES |
Nc1ncnc2c1c(c(CN3CCOCC3)n2C4CCCC4)c5ccc(Oc6ccccc6)cc5
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| InChI |
InChI=1S/C28H31N5O2/c29-27-26-25(20-10-12-23(13-11-20)35-22-8-2-1-3-9-22)24(18-32-14-16-34-17-15-32)33(21-6-4-5-7-21)28(26)31-19-30-27/h1-3,8-13,19,21H,4-7,14-18H2,(H2,29,30,31)
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| InChIKey |
ZSGNCHLJBWLFSG-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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