Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX3JCG
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| Drug Name |
(S)-3-Methyl-2-(3-naphthalen-1-yl-thioureido)-pentanoic acid [(R)-1-formyl-2-(1H-indol-3-yl)-ethyl]-amide
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| Synonyms |
CHEMBL1790994
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C28H30N4O2S
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| Canonical SMILES |
CC[C@@H](C)[C@H](\\N=C(/S)\\Nc1cccc2ccccc12)C(=O)N[C@H](Cc3c[nH]c4ccccc34)C=O
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| InChI |
InChI=1S/C28H30N4O2S/c1-3-18(2)26(32-28(35)31-25-14-8-10-19-9-4-5-11-22(19)25)27(34)30-21(17-33)15-20-16-29-24-13-7-6-12-23(20)24/h4-14,16-18,21,26,29H,3,15H2,1-2H3,(H,30,34)(H2,31,32,35)/t18-,21-,26+/m1/s1
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| InChIKey |
ZDJKOPMEVPPKBM-OFUUFJSKSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin L | Target Info | [1587926] | ||
| Cathepsin B | Target Info | [1587926] | |||
| Reactome | Endosomal/Vacuolar pathway | ||||
| Collagen degradation | |||||
| Degradation of the extracellular matrix | |||||
| Trafficking and processing of endosomal TLR | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentationR-HSA-1442490:Collagen degradation | |||||
| MHC class II antigen presentation | |||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | ||||
| References | |||||
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