Drug Information

Drug General Information
Drug ID
DX2OB3
Drug Name
(+/-)-2-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)-4-chloro-N-(2-(3,4-dichlorophenyl)propyl)benzamide
Synonyms
CHEMBL583457
Indication Discovery agent Investigative [1587926]
Formula
C22H17Cl3N4O3S2
Canonical SMILES
CC(CNC(=O)c1ccc(Cl)cc1NS(=O)(=O)c2cccc3nsnc23)c4ccc(Cl)c(Cl)c4
InChI
InChI=1S/C22H17Cl3N4O3S2/c1-12(13-5-8-16(24)17(25)9-13)11-26-22(30)15-7-6-14(23)10-19(15)29-34(31,32)20-4-2-3-18-21(20)28-33-27-18/h2-10,12,29H,11H2,1H3,(H,26,30)
InChIKey
MBXSGYVYBZBMFK-UHFFFAOYSA-N
Target and Pathway
Target(s) Gastrin/cholecystokinin type B receptor Target Info [1587926]
Cholecystokinin receptor type A Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretionhsa04020:Calcium signaling pathway
Insulin secretion
Pancreatic secretion
PANTHER Pathway CCKR signaling map ST
PathWhiz Pathway Gastric Acid Production
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
Gastrin-CREB signalling pathway via PKC and MAPKR-HSA-375276:Peptide ligand-binding receptors
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Secretion of Hydrochloric Acid in Parietal Cells
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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