Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX2MG6
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| Drug Name |
7-Cyclopentyl-5-(3-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine
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| Synonyms |
CHEMBL69638
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C23H22N4O
|
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| Canonical SMILES |
Nc1ncnc2c1c(cn2C3CCCC3)c4cccc(Oc5ccccc5)c4
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| InChI |
InChI=1S/C23H22N4O/c24-22-21-20(14-27(17-8-4-5-9-17)23(21)26-15-25-22)16-7-6-12-19(13-16)28-18-10-2-1-3-11-18/h1-3,6-7,10-15,17H,4-5,8-9H2,(H2,24,25,26)
|
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| InChIKey |
OWDYYQABYMVBBC-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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