Drug Information

Drug General Information
Drug ID
DX1QFK
Drug Name
4-[(4-Chlorophenyl)methyl]-2-[2-(dimethylamino)ethyl]-1(2H)-phthalazinone
Synonyms
CHEMBL1767134
Indication Discovery agent Investigative [1587926]
Formula
C19H20ClN3O
Canonical SMILES
CN(C)CCN1N=C(Cc2ccc(Cl)cc2)c3ccccc3C1=O
InChI
InChI=1S/C19H20ClN3O/c1-22(2)11-12-23-19(24)17-6-4-3-5-16(17)18(21-23)13-14-7-9-15(20)10-8-14/h3-10H,11-13H2,1-2H3
InChIKey
WRGOSJVRKURGMQ-UHFFFAOYSA-N
Target and Pathway
Target(s) Alpha-1 adrenergic receptor Target Info [1587926]
Histamine H1 receptor Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
PANTHER Pathway Histamine H1 receptor mediated signaling pathway
Reactome Histamine receptors
G alpha (q) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
IL-4 Signaling Pathway
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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