Drug Information
| Drug General Information | |||||
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| Drug ID |
DX1AUW
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| Drug Name |
9-cyclopentyl-6-methyl-12-(tetrahydro-2H-pyran-2-yl)-6,7,8,9-tetrahydro-1H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-3(2H)-one
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| Synonyms |
CHEMBL1085295
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C30H32N4O2
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| Canonical SMILES |
Cn1ncc2c1CCc3c2c4C(=O)NCc4c5c6cc(ccc6n(C7CCCC7)c35)C8CCCCO8
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| InChI |
InChI=1S/C30H32N4O2/c1-33-23-12-10-19-26(21(23)16-32-33)28-22(15-31-30(28)35)27-20-14-17(25-8-4-5-13-36-25)9-11-24(20)34(29(19)27)18-6-2-3-7-18/h9,11,14,16,18,25H,2-8,10,12-13,15H2,1H3,(H,31,35)
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| InChIKey |
OKAGZQCHRAGISN-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 2 | Target Info | [1587926] | ||
| Angiopoietin 1 receptor | Target Info | [1587926] | |||
| NetPath Pathway | IL2 Signaling PathwayNetPath_8:Wnt Signaling Pathway | ||||
| PANTHER Pathway | Angiogenesis | ||||
| VEGF signaling pathwayP00005:Angiogenesis | |||||
| Pathway Interaction Database | HIF-2-alpha transcription factor network | ||||
| Beta3 integrin cell surface interactions | |||||
| Signaling events mediated by TCPTP | |||||
| SHP2 signaling | |||||
| S1P1 pathway | |||||
| VEGF and VEGFR signaling network | |||||
| Integrins in angiogenesis | |||||
| Signaling events mediated by VEGFR1 and VEGFR2 | |||||
| Notch-mediated HES/HEY networkangiopoietinreceptor_pathway:Angiopoietin receptor Tie2-mediated signaling | |||||
| References | |||||
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