Drug Information

Drug General Information
Drug ID
D0ZV0Z
Former ID
DAP000158
Drug Name
Moxifloxacin
Synonyms
Avelox; MFX; MXF; MXFX; Vigamox; Avalox (TN); Avelon (TN); Avelox (TN); Moxifloxacin [INN:BAN]; Vigamox (TN); Avelox I.V.; Actira (*Hydrochloride*); Avelox (*Hydrochloride*); (1'S,6'S)-1-Cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4aS,7aS)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid; 7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxoquinoline-3-carboxylic acid
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Approved [536472]
Therapeutic Class
Antibiotics
Company
Bayer AG
Structure
Download
2D MOL

3D MOL
Formula
C21H24FN3O4
Canonical SMILES
COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O
InChI
1S/C21H24FN3O4/c1-29-20-17-13(19(26)14(21(27)28)9-25(17)12-4-5-12)7-15(22)18(20)24-8-11-3-2-6-23-16(11)10-24/h7,9,11-12,16,23H,2-6,8,10H2,1H3,(H,27,28)/t11-,16+/m0/s1
InChIKey
FABPRXSRWADJSP-MEDUHNTESA-N
CAS Number
CAS 354812-41-2
PubChem Compound ID
152946
PubChem Substance ID
625376, 7980027, 10251676, 14757114, 14781355, 46229296, 46508509, 50042456, 50253020, 57269516, 57347840, 93619768, 96024925, 99289396, 103165320, 104034980, 104435022, 124766236, 126648129, 134337478, 135258896, 135610128, 136293705, 136946518, 137003453, 140146658, 144116250, 152034670, 160825062, 160845926, 160963566, 162174305, 163092436, 163384610, 163644013, 164210139, 164846493, 165245603, 172911637, 175266173, 175438118, 175612185, 176484167, 176485003, 179116798, 184685761, 184812370, 204422851, 210276585, 210281432
SuperDrug ATC ID
J01MA14; S01AE07
SuperDrug CAS ID
cas=151096092
Target and Pathway
Target(s) Bacterial DNA gyrase Target Info Modulator [556264]
Topoisomerase IV Target Info Modulator [556264]
References
Ref 536472Novel agents in the management of Mycobacterium tuberculosis disease. Curr Med Chem. 2007;14(18):2000-8.
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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