Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0ZE1O
|
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| Former ID |
DNCL002638
|
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| Drug Name |
Plinabulin
|
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| Synonyms |
NPI-2358
|
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| Drug Type |
Small molecular drug
|
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| Indication | Non-small cell lung cancer [ICD10:C33-C34] | Phase 2 | [549687] | ||
| Company |
Nereus Pharmaceuticals
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C19H20N4O2
|
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| Canonical SMILES |
CC(C)(C)C1=C(N=CN1)C=C2C(=O)NC(=CC3=CC=CC=C3)C(=O)N2
|
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| InChI |
1S/C19H20N4O2/c1-19(2,3)16-13(20-11-21-16)10-15-18(25)22-14(17(24)23-15)9-12-7-5-4-6-8-12/h4-11H,1-3H3,(H,20,21)(H,22,25)(H,23,24)/b14-9-,15-10-
|
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| InChIKey |
UNRCMCRRFYFGFX-TYPNBTCFSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
14924620, 24220275, 75782763, 99431571, 99437014, 103751458, 109692962, 124490395, 124757055, 125163859, 131480719, 135263531, 136367349, 136946500, 139161543, 144116282, 152258577, 160647412, 162037484, 162202698, 177748748, 184819679, 188899568, 198973468, 223554899, 223679655, 223701041, 223705266, 226458274, 241382117, 249868020, 251970989, 252063684, 252451819
|
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| Target and Pathway | |||||
| Target(s) | Tubulin beta | Target Info | Modulator | ||
| PANTHER Pathway | Cytoskeletal regulation by Rho GTPase | ||||
| Huntington disease | |||||
| References | |||||
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