Drug General Information
Drug ID
D0ZD2M
Former ID
DCL000576
Drug Name
MLN4924
Drug Type
Small molecular drug
Indication Advanced malignancies [ICD9: 140-229; ICD10:C00-C96] Phase 1 [537215]
Company
Takeda
Structure
Download
2D MOL

3D MOL

Formula
C21H25N5O4S
Canonical SMILES
C1CC2=CC=CC=C2C1NC3=NC=NC4=C3C=CN4C5CC(C(C5)O)COS(=O)(=<br />O)N
InChI
1S/C21H25N5O4S/c22-31(28,29)30-11-14-9-15(10-19(14)27)26-8-7-17-20(23-12-24-21(17)26)25-18-6-5-13-3-1-2-4-16(13)18/h1-4,7-8,12,14-15,18-19,27H,5-6,9-11H2,(H2,22,28,29)(H,23,24,25)/t14-,15+,18-,19-/m0/s1
InChIKey
MPUQHZXIXSTTDU-QXGSTGNESA-N
PubChem Compound ID
PubChem Substance ID
Drug Resistance Mutation (DRM)
DRM DRM Info
Target and Pathway
Target(s) NEDD8-activating enzyme Target Info Modulator
References
Ref 537215Drug discovery: Fresh target for cancer therapy. Nature. 2009 Apr 9;458(7239):709-10.

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