Drug General Information
Drug ID
D0Z7IW
Former ID
DNCL002534
Drug Name
JI-101
Drug Type
Small molecular drug
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Phase 2 [532608]
Company
Jubilant Biosys
Structure
Download
2D MOL

3D MOL

Formula
C22H20BrN5O2
PubChem Compound ID
Target and Pathway
Target(s) Receptor protein-tyrosine kinase erbB-4 Target Info Modulator
KEGG Pathway ErbB signaling pathway
Calcium signaling pathway
Endocytosis
Proteoglycans in cancer
PANTHER Pathway Alzheimer disease-presenilin pathway
Cadherin signaling pathway
EGF receptor signaling pathway
WikiPathways ErbB Signaling Pathway
EV release from cardiac cells and their functional effects
References
Ref 532608Therapeutic targeting of EPH receptors and their ligands. Nat Rev Drug Discov. 2014 Jan;13(1):39-62.

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