Drug General Information
Drug ID
D0Z7AN
Former ID
DIB008489
Drug Name
Ro-19-8022
Drug Type
Small molecular drug
Indication Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42] Terminated [544933]
Company
Roche Holding AG
Structure
Download
2D MOL

3D MOL

Formula
C25H21ClN2O3
Canonical SMILES
c1(c2n(c(=O)c(c1)c1ccccc1)ccc1c2cc(cc1)Cl)C(=O)N1[C@@H]<br />(CO)CCC1
CAS Number
CAS 104604-66-2
PubChem Compound ID
Target and Pathway
Target(s) GABA A receptor Target Info Modulator
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 544933Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001584)

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