Drug Information
Drug General Information | |||||
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Drug ID |
D0Z4ZT
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Former ID |
DAP001206
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Drug Name |
Drospirenone
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Synonyms |
DRSP; Dehydrospirorenone; Dihydrospirorenone; Drospirenona; Drospirenonum; Drospirenone [INN]; ZK 30595; ZK30595; Angeliq, Drospirenone; Drospirenona [INN-Spanish]; Drospirenonum [INN-Latin]; SH-470; ZK-30595; Drospirenone (JAN/USAN/INN); (6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-1,3',4',6,6a,7,8,9,10,11,12,13,14,15,15a,16-Hexadecahydro-10,13-dimethylspiro-(17H-dicyclopropa(6,7:15,16)cyclopenta(a)phenanthrene-17,2'(5'H)-furan)-3,5'(2H)-dione; 1,2-Dihydrospirorenone; 1,2-dihydro-spirorenone; 17-Hydroxy-6beta,7beta:15beta,16beta-dimethylene-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid, gamma-lactone; 3-oxo-6alpha,7alpha,15alpha,16alpha-tetrahydro-7'H,16'H-dicyclopropa[6,7;15,16]-17alpha-pregn-4-ene-21,17-carbolactone; 6-beta,7-beta;15-beta,16-beta-Dimethylene-3-oxo-17-alpha-pregn-4-ene-21,17-carbolactone; 6beta,7beta,15beta,16beta-dimethylen-3-oxo-17alpha-pregn-4-en-21,17-carbolacton; 6beta,7beta,15beta,16beta-dimethylene-3-oxo-17alpha-pregn-4-ene-21,17 carbolactone; 6beta,7beta;15beta,16beta-Dimethylene-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone; Spiro(17H-dicyclopropa(6,7:15,16)cyclopenta(a)phenanthrene-17,2'(5'H)-furan)-3,5'(2H)-dione, 1,3',4',6,7,8,9,10,11,12,13,14,15,16,20,21-hexadecahydro-10,13-dimethyl-, (6R-(6alpha,7alpha,8beta,9alpha,10beta,13beta,14alpha,15alpha,16alpha,17beta
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Drug Type |
Small molecular drug
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Therapeutic Class |
Contraceptive Agents
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Structure |
Download2D MOL |
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Formula |
C24H30O3
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InChI |
InChI=1S/C24H30O3/c1-22-6-3-12(25)9-17(22)13-10-14(13)20-16(22)4-7-23(2)21(20)15-11-18(15)24(23)8-5-19(26)27-24/h9,13-16,18,20-21H,3-8,10-11H2,1-2H3/t13-,14+,15-,16+,18+,20-,21+,22-,23+,24+/m1/s1
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InChIKey |
METQSPRSQINEEU-HXCATZOESA-N
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CAS Number |
CAS 67392-87-4
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PubChem Compound ID | |||||
PubChem Substance ID |
8192410, 12014580, 14828605, 14828606, 43125386, 46507653, 47205906, 50047046, 53786814, 56352945, 57317123, 71824971, 76786916, 99437122, 103558411, 104343291, 124757204, 125164008, 126669927, 134338446, 135026678, 135650211, 135692124, 136096480, 136367961, 137005552, 141721609, 143493317, 144115924, 144205769, 152034656, 152233275, 152343982, 160964668, 162176923, 164757002, 170464870, 172089115, 174549055, 175267473, 176484977, 179150909, 184552367, 198991367, 210279219, 210281542, 223678437, 224322273, 226517963, 251915642
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ChEBI ID |
ChEBI:50838
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Target and Pathway | |||||
Target(s) | Mineralocorticoid receptor | Target Info | Binder | [536232] | |
KEGG Pathway | Aldosterone-regulated sodium reabsorption | ||||
PathWhiz Pathway | Kidney Function | ||||
WikiPathways | ACE Inhibitor Pathway | ||||
References | |||||
Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
Ref 539900 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2874). |
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