Drug Information

Drug General Information
Drug ID
D0Z1BQ
Former ID
DIB006562
Drug Name
Cefluprenam
Synonyms
E-1077
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Phase 3 [534476]
Company
Eisai Co Ltd
Structure
Download
2D MOL

3D MOL
Formula
C20H25FN8O6S2
Canonical SMILES
N12C(=O)[C@H]([C@H]1SCC(=C2C(=O)[O-])/C=C/C[N+](CC(=O)N<br />)(CC)C)NC(=O)/C(=N\OCF)/c1nc(sn1)N
CAS Number
CAS 116853-25-9
PubChem Compound ID
6536774
Target and Pathway
Target(s) Bacterial penicillin binding protein Target Info Inhibitor [529176]
References
Ref 534476Usefulness of 7 day therapy with cefluprenam in the management of respiratory tract infections. Kansenshogaku Zasshi. 1997 Aug;71(8):770-87.
Ref 529176Comparison of cefepime, cefpirome, and cefaclidine binding affinities for penicillin-binding proteins in Escherichia coli K-12 and Pseudomonas aeruginosa SC8329. Antimicrob Agents Chemother. 1991 Nov;35(11):2312-7.

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