Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0Z0YB
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| Former ID |
DNC007548
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| Drug Name |
N-benzyl-9-oxo-9,10-dihydroacridine-3-carboxamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [528916] | ||
| Structure |
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Download2D MOL |
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| Formula |
C21H16N2O2
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| Canonical SMILES |
C1=CC=C(C=C1)CNC(=O)C2=CC3=C(C=C2)C(=O)C4=CC=CC=C4N3
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| InChI |
1S/C21H16N2O2/c24-20-16-8-4-5-9-18(16)23-19-12-15(10-11-17(19)20)21(25)22-13-14-6-2-1-3-7-14/h1-12H,13H2,(H,22,25)(H,23,24)
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| InChIKey |
YUICSGTVFUPFFC-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Inosine-5'-monophosphate dehydrogenase 2 | Target Info | Inhibitor | [528916] | |
| PANTHER Pathway | De novo purine biosynthesis | ||||
| References | |||||
| Ref 528916 | J Med Chem. 2007 Jul 26;50(15):3730-42. Epub 2007 Jun 22.Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419). | ||||
| Ref 528916 | J Med Chem. 2007 Jul 26;50(15):3730-42. Epub 2007 Jun 22.Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419). | ||||
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