TTD | Drug: D0Z0KY

Drug General Information
Drug ID	D0Z0KY
Former ID	DIB019962
Drug Name	GSK494581A
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540940]
Structure		Download 2D MOL
Formula	C27H28F2N2O4S
InChI	InChI=1S/C27H28F2N2O4S/c1-18(35-2)20-6-11-26(25(29)16-20)30-12-14-31(15-13-30)27(32)24-17-22(36(3,33)34)9-10-23(24)19-4-7-21(28)8-5-19/h4-11,16-18H,12-15H2,1-3H3
InChIKey	JQXZHDOSMUZLML-UHFFFAOYSA-N
PubChem Compound ID	11855860
PubChem Substance ID	17168588, 23909944, 30178310, 78266418, 141824892, 178102200, 230820596, 246411671
Target and Pathway
Target(s)	G-protein coupled receptor 55	Target Info	Agonist	[531335]
Reactome	Class A/1 (Rhodopsin-like receptors)
Reactome	G alpha (i) signalling events
WikiPathways	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 540940	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5562).
Ref 531335	Pharmacology of GPR55 in yeast and identification of GSK494581A as a mixed-activity glycine transporter subtype 1 inhibitor and GPR55 agonist. J Pharmacol Exp Ther. 2011 Apr;337(1):236-46.

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Drug Information