Drug Information

Drug General Information
Drug ID
D0YU1M
Former ID
DIB011026
Drug Name
G-207 virus construct
Synonyms
HrR3; G-207; G-47; G-47delta; G-207 virus construct, Catherex; G-207 virus construct, MediGene; HSV mutants (glioma), NCI; Oncolytic herpes simplex virus (glioma), Catherex/MediGene
Indication Glioma [ICD9: 191; ICD10:C71] Phase 1/2 [521499]
Company
MediGene Inc
CAS Number
CAS 126098-20-2
Target and Pathway
Target(s) Ribonucleoside-diphosphate reductase Target Info Inhibitor [527093], [531689]
References
Ref 521499ClinicalTrials.gov (NCT00028158) Safety and Effectiveness Study of G207, a Tumor-Killing Virus, in Patients With Recurrent Brain Cancer. U.S. National Institutes of Health.
Ref 527093Utilizing tumor hypoxia to enhance oncolytic viral therapy in colorectal metastases. Ann Surg. 2004 Jun;239(6):892-9; discussion 899-902.
Ref 531689Anti-tumor effect of oncolytic herpes simplex virus G47delta on human nasopharyngeal carcinoma. Chin J Cancer. 2011 Dec;30(12):831-41.

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