Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0YO7Y
|
||||
| Former ID |
DIB007042
|
||||
| Drug Name |
DAS-181
|
||||
| Synonyms |
Fludase; NEX-DAS-181; Enzyme-based therapy (Tosap, influenza), NexBio
|
||||
| Indication | Influenza virus [ICD10:J11.1] | Phase 2 | [1] | ||
| Company |
Nexbio
|
||||
| Target and Pathway | |||||
| Target(s) | Neuraminidase | Target Info | Inhibitor | [2], [1] | |
| KEGG Pathway | Other glycan degradation | ||||
| References | |||||
| REF 1 | Inhibition of neuraminidase inhibitor-resistant influenza virus by DAS181, a novel sialidase fusion protein. PLoS One. 2009 Nov 6;4(11):e7838. | ||||
| REF 2 | Neuraminidase inhibitors: zanamivir and oseltamivir. Ann Pharmacother. 2001 Jan;35(1):57-70. | ||||
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