Drug Information
Drug General Information | |||||
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Drug ID |
D0Y8ZN
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Former ID |
DCL000582
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Drug Name |
Ofatumumab
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Synonyms |
Arzerra (TN)
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Drug Type |
Antibody
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Indication | Chronic lymphocytic leukaemia [ICD10:C91] | Approved | [530677], [541858] | ||
Diffuse large B-cell lymphoma; Multiple sclerosis [ICD9: 202.8, 340; ICD10:C85.1, G35] | Phase 3 | [530677], [541858] | |||
Rheumatold arthritis; Follicular lymphoma [ICD9: 202.0, 714; ICD10:C82, M05-M06] | Phase 2 | [530677], [541858] | |||
Company |
GlaxoSmithKline
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Structure |
Download2D MOL |
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Formula |
C12H10N4O2
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PubChem Compound ID | |||||
SuperDrug ATC ID |
L01XC10
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Target and Pathway | |||||
Target(s) | B-lymphocyte antigen CD20 | Target Info | [530677], [550963] | ||
KEGG Pathway | Hematopoietic cell lineage | ||||
References | |||||
Ref 530677 | Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92. | ||||
Ref 541858 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6778). |
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