Drug General Information
Drug ID
D0Y8ZN
Former ID
DCL000582
Drug Name
Ofatumumab
Synonyms
Arzerra (TN)
Drug Type
Antibody
Indication Chronic lymphocytic leukaemia [ICD10:C91] Approved [530677], [541858]
Diffuse large B-cell lymphoma; Multiple sclerosis [ICD9: 202.8, 340; ICD10:C85.1, G35] Phase 3 [530677], [541858]
Rheumatold arthritis; Follicular lymphoma [ICD9: 202.0, 714; ICD10:C82, M05-M06] Phase 2 [530677], [541858]
Company
GlaxoSmithKline
Structure
Download
2D MOL

3D MOL

Formula
C12H10N4O2
PubChem Compound ID
SuperDrug ATC ID
L01XC10
Target and Pathway
Target(s) B-lymphocyte antigen CD20 Target Info [530677], [550963]
KEGG Pathway Hematopoietic cell lineage
References
Ref 530677Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
Ref 541858(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6778).
Ref 530677Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92.
Ref 550963Clinical pipeline report, company report or official report of GlaxoSmithKline (2009).

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